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Surgical Innovation
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Article

Patient Mood and Neuropsychological Outcome After Laparoscopic and Conventional Colectomy

Magdalena Gameiro, Wolfgang Eichler, Oliver Schwandner, Ralf Bouchard, Julika Schön, MD, Peter Schmucker, Hans-Peter Bruch, and Michael Hüppe, Ph.D*

* To whom correspondence should be addressed. E-mail: hueppe{at}mail.uni-luebeck.de.


  Abstract
The study was designed to compare patients after laparoscopic and conventional colectomy with regard to early postoperative mood, cognitive function, and neurocognitive variables S100{beta} and neuron-specific enolase (NSE). Forty-five laparoscopic and 25 open colectomies were enrolled into the prospective study. Outcome measurements were positive and negative postoperative mood (BSKE), neuropsychological tests (Trail-Making Test; word reproduction; Stroop Test), and serum biochemical parameters (S100{beta}; NSE). Following laparoscopic procedure, patients described significantly better positive mood (P < .05), tended to require less time in the Trail-Making Test and Stroop Test, and had lower postoperative serum concentrations of S100{beta} compared to conventional colectomy patients (P < .01). The current results revealed several group differences, which, in their entirety, seem to represent a more beneficial outcome after laparoscopic colonic surgery.

First published on July 3, 2008, doi:10.1177/1553350608320554

Surgical Innovation 2008;15:171.

A more recent version of this article appeared on September 1, 2008

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