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Surgical Innovation
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Emerging Techniques for Optical Detection of Early Mucosal Cancer

E. Luke Newman, PhD, MA

Department of Surgery, Uniuersity of Dundee, Ninewells Hospital and Medical School, Dundee, UK

Iain S. Tait, MBChB, FRCS, PhD

Department of Surgery, Uniuersity of Dundee, Ninewells Hospital and Medical School, Dundee, UK

Most methods of optical detection of gastrointestinal cancer are aimed at improving the contrast between malignant lesions and normal or metaplastic tissue. Although almost any optical property of matter can theoretically be exploited in this manner, recent work has focused on the use of exogenous fluorescent substances or their metabolic precursors to provide this contrast.

Key Words: Metaplasia • dysplasia • cancer • endoscopy • fluorescence • 5-aminolaevulinic acid.

Surgical Innovation, Vol. 4, No. 2, 80-88 (1997)
DOI: 10.1177/155335069700400204
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